Table 3 Characteristics of included studies
| Study ID | Teeth | Intervention method | Evaluation intervals | Pain measure method |
|---|---|---|---|---|
| Celestino No´brega 2013 | mesial and distal sides of the first permanent lower molars on the left and right sides | each subject received irradiation one spot on the region of root apex, three points along the root axis on the buccal side | 2 h,6 h,24 h,3 d,5 d | VAS ;The incidence of free of pain |
| Won Tae Kim 2012 | mesially and distally on both of the maxillary first molars. | apply laser for 30 seconds on each area immediately then every 12 hours for 1 week with close contact between the tip and mucosa to irradiate the mesiobuccal, mesiolingual, distobuccal, and distolingual areas. | 5 min,1 h,6 h,12 h,1 d,2 d,3 d,4 d,5 d,6 d,7 d | VAS |
| Ladan Eslamian 2013 | first permanent molars (distal and mesial),either on maxillary (22 patients) or mandibular (15 patients) arches | laser irradiation on the buccal side (at the cervical third of the roots), for distal and mesial of the second premolars and first permanent molars, as well as distal of second permanent molars (five doses) . The same procedure was repeated for the lingual or palatal side (five doses). After 24 h, patients returned to the clinic and received another 10 doses of laser irradiation on the same quadrant. | 0 h,6 h,24 h,30 h,3 d,4 d,5 d,6 d,7 d | VAS |
|
Esper MA 2011 | Placebo :mesial and distal of the first upper and lower molar on the right side while the Laser group on left side | Radiation was applied punctually, touching the gum perpendicularly on two points of the vestibular side and on the lingual side of the separated molars, both points were in the cervical and radicular region | pre-placement 2 h,24 h,48 h,72 h,96 h | VAS |
|
Ida Marini 2013 | right first ,second premolar and first molar (upper arch or lower arch) | The laser probe was applied on the cervical third of buccal and lingual gingiva l covering of each root. | 0 h,12 h,24 h,36 h,48 h,72 h,96 h | VAS,Questionnaire |
|
Zhang HY 2014 | First molar | the laser probe was 5 mm away from the mucosal ,Laser irradiation was applied on first molar root apical ,then Move up along the long axis of the tooth to the tooth neck (totally 4 points) | 2 h,6 h,24 h,72 h,120 h | VAS |