Effects of estrogen deficiency during puberty on maxillary and mandibular growth and associated gene expression – an μCT study on rats

Table 4 Gene expression in the growth sites assessed

Growth sites	*Groups*	RANK		RANKL		OPG		RANKL:OPG
Growth sites	*Groups*	Mean (SD)	p-value	Mean (SD)	p-value	Mean (SD)	p-value	Mean (SD)	p-value
Midpalatal suture	*OVX*	0.40 (0.08)	0.036*	1.22 (0.54)	0.239	0.85 (0.18)	0.306	1.40 (0.96)	0.313
Midpalatal suture	*Sham-operated*	0.67 (0.02)	0.036*	0.65 (0.05)	0.239	0.68 (0.06)	0.306	0.96 (0.16)	0.313
Condyle	*OVX*	1.80 (1.48)	0.174	1.57 (0.84)	0.061	0.35 (0.13)	0.868	4.48 (1.61)	0.015*
Condyle	*Sham-operated*	0.44 (0.07)	0.174	0.40 (0.14)	0.061	0.37 (0.16)	0.868	1.17 (0.43)	0.015*
Mandibular angle	*OVX*	0.43 (0.13)	0.191	0.41 (0.03)	0.209	0.41 (0.11)	0.136	1.02 (0.19)	0.588
Mandibular angle	*Sham-operated*	0.27 (0.16)	0.191	0.28 (0.18)	0.209	0.28 (0.10)	0.136	0.93 (0.24)	0.588
Symphysis / parasymphysis	*OVX*	0.62 (0.56)	0.806	1.00 (0.56)	0.451	1.05 (0.36)	0.453	0.92 (0.40)	0.804
Symphysis / parasymphysis	*Sham-operated*	0.35 (0.43)	0.806	0.65 (0.06)	0.451	0.77 (0.44)	0.453	1.04 (0.68)	0.804
Coronoid process	*OVX*	0.43 (0.14)	0.412	0.39 (0.14)	0.904	0.29 (0.09)	0.703	1.37 (0.34)	0.285
Coronoid process	*Sham-operated*	0.33 (0.09)	0.412	0.34 (0.11)	0.904	0.32 (0.06)	0.703	1.06 (0.33)	0.285

ISSN: 1746-160X